# Labcorp / OmniSeq

Labcorp's OmniSeq INSIGHT reads tumor DNA and RNA, plus other biomarkers, to inform treatment and clinical trial discussions. Your doctor orders it using stored tumor tissue.

Author: Kevin Wimer
Canonical URL: https://kevinwimer.com/cancer/organizations/labcorp-omniseq/
Stable ID: b0a3681f-7e79-4f74-8d33-b31fdb6121fa
Revision: b7772f2e-ea36-4d0a-9c2b-67eedee354de
Published: 2026-10-26T21:36:35.644Z
Updated: 2026-10-26T21:36:35.644Z
Reviewed: 2026-10-26

## Who this is for
People with solid tumors whose doctors are considering molecular testing to inform treatment or clinical trial discussions. The exact test and sample must fit the clinical question.

Labcorp's OmniSeq INSIGHT tests tumor tissue for DNA and RNA changes, plus markers that may help your doctor discuss targeted drugs, immunotherapy and clinical trials. Your doctor orders it.

## What they do

OmniSeq INSIGHT combines a 523-gene DNA panel, RNA testing for fusions, and other biomarkers in one report. It includes PD-L1 protein testing, microsatellite instability (MSI) and tumor mutational burden (TMB). These are different measurements; ask which ones matter for your cancer.

## Who it's for

People with solid tumors whose doctors want comprehensive tumor profiling. This profile covers OmniSeq INSIGHT, rather than every Labcorp cancer test.

## How to start

Your doctor sends the order, pathology report and other required records. Labcorp can request stored tissue from the facility holding it.

The preferred sample is a preserved tumor tissue block. Slides may also be accepted. Labcorp says not to send decalcified samples, cytology smears or samples from blood cancers for this test. Have pathology confirm the requirements before shipping.

## Cost and insurance

As of October 2026, the pages checked did not list a fixed patient price for OmniSeq INSIGHT. Labcorp offers payment plans and financial hardship programs. Its Oncology Services Team handles testing assistance for this test. Ask for a coverage check and expected bill before the sample goes out.

## Other options

[Caris](/cancer/organizations/caris-life-sciences/), [Tempus](/cancer/organizations/tempus/) and [Foundation Medicine](/cancer/organizations/foundation-medicine/) also offer tumor profiling. Compare what the exact test reads and whether it can use the tissue you already have.

## What to ask

1. What would this add to my existing tumor testing?
2. Is my stored tissue suitable, and how much will testing use?
3. Does the RNA analysis cover the fusions we need to check?
4. What will I owe, and should I apply for assistance first?

Finding a biomarker does not guarantee that a treatment will work or that a trial can accept you.

## Contacts

- Test details and ordering: [OmniSeq INSIGHT](https://www.labcorp.com/oncology/providers/testing-solutions/test-menu/omniseq-insight)
- Financial assistance: [Labcorp Oncology](https://www.labcorp.com/oncology/patients/financial-assistance)
- Testing assistance: 800-844-8121
- Client Services: 800-345-4363

## Limits and context
This profile covers tissue-based OmniSeq INSIGHT. Sample restrictions apply. Genomic findings do not guarantee treatment benefit or trial eligibility.

## Relationships and disclosures
I have no financial or business relationship with Labcorp / OmniSeq.

## Sources
- [OmniSeq INSIGHT: test details and ordering](https://www.labcorp.com/oncology/providers/testing-solutions/test-menu/omniseq-insight) — Labcorp; official; checked 2026-10-26; Solid-tumor tissue DNA/RNA profiling, biomarkers, ordering, tissue procurement, sample exclusions, reports and client services.
- [Labcorp Oncology financial assistance](https://www.labcorp.com/oncology/patients/financial-assistance) — Labcorp; official; checked 2026-10-26; Payment plans and financial hardship support; specific OmniSeq INSIGHT assistance phone number.
- [Biomarker testing for cancer treatment](https://www.cancer.gov/about-cancer/treatment/types/biomarker-testing-cancer-treatment) — National Cancer Institute; official; checked 2026-10-26; Tumor profiling can inform treatment and trial discussions; testing does not guarantee an actionable result or treatment benefit, and inherited-risk testing answers a different question.

Organization website: https://www.labcorp.com/

Organization type: Company

Services: Genomic testing

Information/access: [OmniSeq INSIGHT information](https://www.labcorp.com/oncology/providers/testing-solutions/test-menu/omniseq-insight)

Service status: available

## Company facts
- **Test:** OmniSeq INSIGHT combines tumor DNA/RNA testing with MSI, TMB and PD-L1 assessment for solid tumors. (Sources: labcorp-insight)
- **Samples:** Preserved solid-tumor tissue block preferred; slides may be accepted. Decalcified samples, cytology smears and blood-cancer samples are excluded. (Sources: labcorp-insight)
- **Ordering:** Your doctor submits the order and pathology report. Labcorp can arrange retrieval of stored tissue. (Sources: labcorp-insight)
- **Cost:** As of October 2026, no fixed patient price was found on the pages checked. Ask for a coverage check, estimate and financial assistance information. (Sources: labcorp-assistance, labcorp-insight)

Topics: tumor-testing
Capabilities: tumor-testing

Related record IDs: 47f21cb6-8618-4ac9-8677-d670b06a4637, 5c806cbb-c7b3-443a-8a44-e0e6c559a196, 3c7420d0-44d6-461d-8faf-3a9d170e61b9, f7221927-6b87-4be3-9a7c-906768a192a5

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Educational information, not an individualized treatment recommendation.